Sleep disturbances were not reported at notably higher rates in the semaglutide groups compared to placebo groups, and insomnia is not listed as a common adverse reaction in the UK SmPC
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10 In large adult randomized controlled trials, tirzepatide demonstrated substantial weight-loss efficacy, with mean body weight reductions of up to 20.9% over 72 weeks, surpassing outcomes observed with semaglutide monotherapy
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