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Semaglutide works by slowing stomach emptying and signaling fullness to the brain, yet some patients report weight gain or plateaus after initial success
Yamada H, Takuma N, Daimon T, Hara Y
6 Some reviews suggest GLP-1s may even offer comparable or slightly better muscle preservation than diet-only approaches
The trade-offs are higher cost, aneesthesia, recovery time, and surgical risks
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