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doi:10.1016/S2666-5247(23)00221-5
Many patients may find 8mg sufficient and not need to escalate to 12mg, especially if side effects are well-controlled at 8mg
Through these mechanisms, semaglutide ensures better blood sugar control and significantly diminishes appetite, aiding in weight loss
Early data from this trial have shown encouraging results in terms of glucose and body weight reduction
these effects may be mediated indirectly rather than via direct brain action, since semaglutide may have limited ability to cross the BBB [49]
Therapy duration and post-discontinuation weight regain The optimal duration of GLP-1based multi-agonist therapy remains to be established
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