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(PubMed) Schoenfeld JD, Sibenaller ZA, Mapuskar KA, et al

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After the signal is cleaved, the resulting unique precursor pro-GGT is modified through a self-proteolytic cleavage event termed autoprocessing, forming an active mature heterodimer of large and small subunits (Tate and Meister, 1981

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Traditional urine analysis does not detect doping with HGH, so the ban was not enforced until the early 2000s, when blood tests that could distinguish between natural and artificial HGH were starting to be developed

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