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TMAO and atherosclerosis Atherosclerosis, which is the major risk factor of CVDs, is characterized by foam cell formation, inflammatory cell recruitment, and endothelial dysfunction ( Figure 3 )
Refinement was performed using Refinement embedded in the PHENIX suite 76,77
56 The MNAM together with their oxidized compounds, 4py and 2py, are eventually eliminated in the urine
With respect to the SOUL trial, oral semaglutide demonstrated a 14% reduction in MACE outcomes, independent of concurrent SGLT2 inhibitor use
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