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This is why formulation design is so critical

doi:10.1074/jbc.M211558200 Li MH, Cha YN, Surh YJ (2006) Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells

ZhaoLWangCSongDLiYSongYSuGet alSystemic administration of the antioxidant/iron chelator alpha-lipoic acid protects against light-induced photoreceptor degeneration in the mouse retina

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On the other hand, turbulent flow refers to the irregular, oscillatory mechanical forces created by disturbed blood flow at arterial branches, bends, and dysfunctional venous valves [206]

Snyder PJ, Bhasin S, Cunningham GR, et al