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Injection typically offers faster absorption and more predictable dosing, while oral provides convenience for injection-averse patients

Visual inspection catches most problems before injection

The definition of renal outcomes across these in these trials varied, but included measures such as incident or worsening nephropathy (progression to macroalbuminuria, doubling of the serum creatinine level, initiation of renal replacement therapy, or death from renal disease) and incident albuminuria (86,90)

Standardize all references to rhythm impairment as circadian disruption, unless a specific subtype (e.g., phase advance, amplitude dampening) is discussed

Step 5 Keeping the needle in the vial, turn the vial upside down