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Summary: Dulaglutide and extended-release GLP-1 formulations generally demonstrate lower nausea rates compared to twice-daily exenatide or higher-dose semaglutide and liraglutide, though individual responses vary considerably

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proposed lactate as the primary carbon source in the TCA cycle [130]

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Some studies show it can improve blood sugar control and reduce weight gain in ways that overlap with GLP-1 pathways