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PMID 15043988

Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner

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Nevertheless, a phase III study found no significant differences in cognition between rosiglitazone treatment and placebo in APOE-4-non-carriers or overall [37]

If youre squeamish around needles, for example, phentermine/topiramate may be a better option