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Novel propargyl-linked bisubstrate analogues as tight-binding inhibitors for nicotinamide N-methyltransferase
J Clin Investig 2010
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A substantial number of patients do not respond adequately to traditional agents [9], and the non-response rate is estimated to be higher in the immuno-metabolic phenotype [147]
Published online October 14, 2024
The team say the findings support the importance of long-term maintenance of weight reduction through lifestyle intervention and obesity management medications to sustain cardiometabolic benefits and improved health-related quality of life
