379 GLP-1RAs, particularly PF1801, have demonstrated effective relief in inflammatory myopathies, such as polymyositis (PM), through preclinical studies
No anhedonia or fatigue : A documented side effect from these meds is anhedonia, the blunting of pleasure/joy, and some users report fatigue
[3] The British Society for Haematology guidelines emphasise that the response to treatment should be monitored through clinical assessment and blood count testing, rather than routine measurement of B12 levels after treatment has started
I was scared too
Many GPCRs, including GLP-1R and GIPR, couple to the stimulatory G protein, Gs, to activate adenylyl cyclase and produce the second messenger cyclic AMP
NICE does not recommend it on the NHS due to insufficient evidence and the absence of a UK marketing authorisation