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To date, remission of T2D has been associated by reduction of liver and pancreas ectopic fat accumulation and restored insulin secretion 76

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Too often, people wrongly think obesity is the fault of the individual, when in reality some people have a strong genetic predisposition for it, says Aaron Kelly, PhD, codirector of the Center for Pediatric Obesity Medicine at the University of Minnesota Medical School

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PMID: 39521378.

These four foundational therapies should be initiated early, and recent data suggest that an early up-titration within 6 weeks improves the prognosis compared to a standard approach [23]