Known by its brand name, Wegovy, Semaglutide is a medication classified as a glucagon-like peptide-1 (GLP-1) receptor agonist
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Researchers reported that the results across all three trials indicated that the peptide may have a positive correlation with exposure and melanin production, as observed on a cellular level and in the relative tanning gradation
It is also interesting to me that the use of anticholinergics with GLP-1 agonists doesnt flag as a potential drug even though both can worsen/exacerbate gastroparesis
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Given the secondary nature of this study and the number of statistical tests, we did not look at possible clinical/behavioral implications of these endocrine effects a relevant question that was beyond the scope of the present study and should be explored in the future