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Patients with documented gallstones should discuss with their healthcare team whether to continue semaglutide, as the decision depends on individual circumstances including symptom severity, weight loss goals, glycemic control needs, and surgical candidacy
Retrieved January 7, 2026
Research published in Obesity (2023) found that patients discontinuing GLP-1 agonists without tapering regained 3050% of lost weight within 6 months
A 60-year-old women with a 40-year history of refractory Hailey-Hailey disease and type 2 diabetes received liraglutide 1.8 mg SC for 6 months, after which she had near complete resolution of lesions on her neck, axillae, and inguinal and abdominal folds as well as resolution of associated pain
It could be an enzyme called NNMT that is telling your fat cells to store more and burn less