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Genetic Influences and Complex Pathways The gut microbiotas first step in converting unabsorbed carnitine into TMA is generation of the intermediate gamma-butyrobetaine (GBB), which has been shown to be atherogenic in mice, although research in humans is inconclusive

Am J Health Syst Pharm

13 : 909916 Aureli T, Miccheli A, Ricciolini R, Di Cocco ME, Ramacci MT, Angelucci L et al

It also serves to regulate activities of vital organs and blood vessels, as well as communication between nerves and muscles

(2003) 44:S141