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In vivo preclinical models investigating glucose regulation, body weight, cardiovascular parameters, and inflammatory responses through GLP-1R pathways, hypothalamic signaling, and cytokine modulation

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The GLP-1 analogs liraglutide and semaglutide reduce atherosclerosis in ApoE / and LDLr / mice by a mechanism that includes inflammatory pathways

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Doses vary from 500 to 3,000 mg per day

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