Formulation, characterization, and advantages of using liposomes in multiple therapies
In 2020, Eli Lilly developed the dual-action drug, injectable tirzepatide administered once weekly (Mounjaro for type 2 diabetes and Zepbound for weight management) that activates both GLP-1 and GIP receptors
10.26355/eurrev_201808_15723 29 ChenJ.MangelinckxS.AdamsA.WangZ
The peptide exhibits anabolic and metabolic activities through IGF-1 receptor binding, though it has never been approved for therapeutic human use and remains confined to research applications [12]
Consequently, AI-assisted platforms such as CRISPR AI and sgRNA Designer facilitate the selection of guide RNAs with improved efficiency and specificity, thereby increasing editing success while reducing experimental costs and screening requirements (Dai et al., 2024)
However there is a lot of red tape on how to do it correctly