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Cells with imbalanced proliferation and apoptosis maintain a proliferative advantage through metabolic reprogramming, characterized by enhanced glycolysis and disrupted redox homeostasis (Zhou et al., 2024)

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Is it a common acquired nevus, melanoma, an oral melanotic macule, or a blue nevus

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Dehydration represents another important contributor, as reduced oral intake due to nausea or early satiety combined with gastrointestinal losses can lead to volume depletion

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