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To view or add a comment, sign in Albuterol (Salbutamol) Class: Short-acting beta-2 adrenergic receptor agonist (SABA) Bronchodilator Mechanism of Action Stimulates beta-2 adrenergic receptors in bronchial smooth muscle Increases cAMP activates protein kinase A relaxation of smooth muscle bronchodilation Uses Acute relief of bronchospasm in: Asthma Chronic obstructive pulmonary disease (COPD) Exercise-induced bronchoconstriction (EIB) Hyperkalemia (off-label: shifts potassium into cells temporarily) Routes of Administration Inhalation (preferred): Metered-dose inhaler (MDI), nebulizer Oral: Tablets or syrup (less preferred due to systemic effects) IV: Rarely, in severe status asthmaticus Dosage (Typical) Inhalation (adults/children 4 years): 90180 mcg (12 puffs) every 46 hours as needed Nebulizer: 2.5 mg every 20 minutes 3 doses, then 2.5 mg every 24 hours as needed Adverse Effects Tremors (most common) Tachycardia, palpitations Nervousness, headache Hypokalemia (especially with high doses) Rare: arrhythmias, paradoxical bronchospasm Precautions / Contraindications Use caution in patients with cardiac disease, arrhythmias, hypertension Avoid overuse tolerance and decreased effectiveness Monitor for hypokalemia in severe asthma exacerbations SABA = rescue inhaler for acute asthma symptoms Quick onset (~5 minutes), short duration (~46 hours) Side effects: tremor and tachycardia Can be used temporarily in hyperkalemia to shift K into cells First-line therapy for acute bronchospasm To view or add a comment, sign in Im Excited to share our new open-access review in Diabetes, Obesity & Metabolism: Diabetic kidney disease, biomarkers, and finerenone. Why this matters: Diabetic kidney disease (DKD) affects ~3040% of people with diabetes and remains the leading cause of kidney failure worldwide, tightly linked to cardiovascular risk

Comparative effects of weight loss and incretin-based therapies on vascular endothelial function, fibrinolysis and inflammation in individuals with obesity and prediabetes: a randomized controlled trial