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However, these effects were observed only in the intention-to-treat analysis, not the per-protocol population

Yes, but it requires a cold chain

(Bures 2010) While the gold standard of diagnosis is intestinal aspiration, breath tests using glucose or lactulose may also be used to test for hydrogen-dominant SIBO (H-SIBO) or methane-dominant SIBO (M-SIBO), with widely varying sensitivities and specificities

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This is referred to as the lipid bilayer

doi:10.4062/biomolther.2024.182 Lee HY, Lee GH, Kim DS, et al