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By mimicking the action of the naturally occurring GLP-1 hormone, semaglutide works to enhance insulin secretion in response to meals, decrease glucagon release, and slow gastric emptying, all of which contribute to better blood sugar management
Expert review of endocrinology & metabolism, 20(6), 441443
doi:10.1017/S0029665107005563 Hedin C, Whelan K, Lindsay JO
Medical relevance of common protein-altering variants in GPCR genes across 337,205 individuals in the UK Biobank