The treatment typically begins with a lower starting dose, usually 0.25 mg once weekly
Adjustments to other diabetes medications may be necessary to maintain glycemic control
Imane Hachemi 1 , Mueez U-Din 1,2 Endocrinology and Metabolism 2023;38(2):214-222
In contrast, several polysaccharides have been proven to reduce cisplatin resistance ( Angelica sinensis polysaccharide (ASP) combined with cisplatin increased ferroptosis in cisplatin-resistant ovarian cancer cells through inhibition of GPX4 expression with significant GSH depletion and no obvious toxicity to liver, kidney, and cardiac tissues, ultimately reversed the resistance to cisplatin ( Lotus seedpod polysaccharides (LSP) combined with cisplatin induced ferroptosis in hepatocellular carcinoma via GSH-dependent pathway (Fu et al., 2021)
Sample preparation was conducted using a proprietary (Metabolon, Durham, North Carolina, USA) series of organic and aqueous extractions to remove the protein fraction while allowing maximum recovery of small molecules
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