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It acts by mimicking the endogenous hormone ghrelin and binding to the growth hormone secretagogue receptor type 1a (GHS-R1a) in the anterior pituitary gland

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For researchers and clinicians following this issue, this is the central question in the upcoming FDA decision: is dysesthesia frequent and debilitating enough to justify a special mention in the indications, or even a 12 mg dose reserved for specific patients

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Rotate between at least six to eight specific locations to prevent lipohypertrophy, the development of fatty tissue lumps that can form with repeated injections at the same site

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