Mitochondrial carriers (MCs) are a group of transport proteins located in the mitochondrial membrane and primarily responsible for mediating the translocation of metabolites between mitochondria and the cytoplasm, which is indispensable for modulating metabolic activities and maintaining homeostatic balance [9, 10]
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Replacing glucose with galactose severely depletes de novo purine biosynthesis pathway intermediates in both control and KO cells (Fig
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