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Electrostatic similarity analysis Electrostatic similarity calculations were performed using OpenEye toolkit by combining ROCS for shape-based alignment and EON for electrostatic similarity calculations

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Ratios of log 2 -normalized transcript count data were generated for SLD Dpp4 / mice versus baseline SLD WT mice, HFHC-fed Dpp4 / mice versus baseline HFHC-fed WT mice, and HFHC-fed Dpp4 hep/ mice versus baseline HFHC-fed Dpp4 GFP mice

While diabetes and obesity pose many of the same risks to the body, they arent exactly the same, so its hard to know whether that also influenced the results

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