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In particular, isolate N.9516 contained csxABC genes that shared 98% amino acid identity with the meningococcal serogroup X reference strain 388, while isolate N.17716 contained cssABC-csb genes that shared 99% amino acid identity with the meningococcal serogroup B reference strain H44/76 (Mustapha et al., 2020)

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The timeframe for observing results also plays a role short-term effects might call for a single, higher dose, while long-term studies may benefit from smaller, repeated doses

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