The MHRA issued a Drug Safety Update in January 2025 about monitoring and managing gastrointestinal side effects with tirzepatide
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Licensed oral weight management options in the UK include orlistat
Known brands include Wegovy, celebrated for weight management, and Ozempic, famous for managing type 2 diabetes
New or worsening symptoms should be evaluated, but many changes are unrelated to the medication itself
In the SURMOUNT-1 trial, tirzepatide at 15 mg weekly resulted in up to 22.5% body weight reduction over 72 weeks (Jastreboff et al., 2022)