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TRT maintains the hormonal environment necessary to retain muscle

Redox homeostasis, oxidative stress and mitophagy

When common confounders were removed, GLP-1 therapy showed no independent link to pancreatitis

Markers such as lipids, ApoB, hs-CRP, ALT, AST, and GGT can help provide a broader picture of metabolic improvement

More dramatic weight loss A landmark retrospective head-to-head study comparing bariatric procedures (like sleeve gastrectomy or gastric bypass) with GLP-1 injections found that surgery patients lost about five times more weight over two years than those on GLP-1 therapy

10.1056/NEJMra1900500 8 CelliB.LocantoreN.YatesJ