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I started shots recently, with proper diet and activity Im down approximately 13 lbs in going into 4th week

Specifically, the HR for HHF was 0.20 (95% CI 0.070.60) with GLP-1RAs and 0.77 (95% CI 0.640.92) without GLP-1RAs ( P -value for interaction 0.014)

When clients ask me whether they should use a GLP-1 medication to lose the last 5 to 10 pounds, I come back to the same question: To what end

In individuals with type 2 diabetes, another phase 2 clinical study demonstrated that after 12 weeks of efinopegdutide treatment, although no significant improvement in glycated hemoglobin (HbA1c) levels was observed, the effect on weight loss reached a high of 7.9%, well above the 0.7% weight reduction rate in the placebo group

Ethics declarations Ethics approval All animal procedures were conducted in accordance with the guidelines established by the National Institutes of Health Guide for the Care and Use of Laboratory Animals and were approved by the Institutional Animal Care and Use Committee (IACUC) at the University of Maryland School of Medicine (protocol number 00000006)

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