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Indeed GDH can also incorporate the amide derived 15N ammonium and alpha ketoglutarate into glutamate (Figure 1,, reductive amination) which can subsequently transaminate with pyruvate generating 15N alanine [3]

This does not indicate failure

On the contrary, the stable clone and wild type did not show any significant difference in their susceptibility towards doxorubicin (3 g/ml)- or radiation (0.21 Gy)-induced cell death

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