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or by rectal surgery

There are reported concerns about potential adverse effects and complications associated with these medications during surgery and patients on daily dosing are advised to consider withholding GLP-1RA the day of the procedure

Current clinical evidence for possible antidepressant effects of GLP-1R agonists Depression is often comorbid with metabolic disorders such as T2DM and obesity and many antidiabetic drugs, which often display neuroprotective and immunomodulatory effect, have demonstrated antidepressant properties in clinical trials

Medicare law still excludes drugs prescribed only for weight loss

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