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Acquired oral hyperpigmentation can, in rare cases, be associated with malignancy including oral melanoma
Circ Res 118(1):145156
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And really, they work and theyre very safe, with very, very, very few contraindications [i.e
From a molecular medicine and cardiovascular research perspective, the mechanistic overlap is particularly compelling, especially considering shared drivers like insulin resistance, systemic inflammation, and lipid dysregulation
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