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Obese patients, have been reported to produce more SCFAs in their intestines (310), but indeed meaningful diet-induced shifts in SCFA production fluxes have proven not sufficient to modulate peripheral levels of GLP-1 and PYY (311)

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Discuss fertility plans with your GP or specialist to ensure safe discontinuation timing and appropriate contraception whilst on treatment

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Expect irregular cycles during rapid weight loss phase, typically heavier or lighter flow, cycle length changes of 3-7 days, or temporary absence of periods if losing weight very quickly

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