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Specifically, an increase in PUFAs of the TG category was observed in ethanol-fed GCLM KO mice

Remogliflozin (Remo) is an FDA-approved SGLT2 I (Markham, 2019)

Proper cellular hydration depends on the function of aquaporinsspecialized water channel proteins that regulate water transport across cell membranes

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The study also found reductions in liver fat as measured by controlled attenuation parameter (CAP scores), plus improvements in triglycerides and other metabolic markers

Gene expression analysis Total RNA was extracted using RNeasy (Qiagen