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One simple hypothesis is that greater antibody titres in severe COVID-19 cases result from higher and more prolonged antigen exposure due to higher viral loads 48,49
Theres also a safety point worth stating plainly
Veterinary immunology and immunopathology
Radiat Res 155:536542
This study was supported by the Genome Tagging Project and grants from the National Natural Science Foundation of China (32488101, 32370909, 32293231, 32470632, 32030029, and 92253302), the National Key R&D Program of China (2024YFA1800010), the CAS Strategic Priority Research Program B (XDB0990000), the Shanghai Municipal Science and Technology Major Project (23HC1401000), the National Science and Technology Innovation 2030 Major Project of China (2023ZD0500502 and 2021ZD0203900), and by the Medical Research Council of the UK (MR/T003162/1 to I.C.)
Topical application of a glutathione amino acid precursor formulation to ex vivo skin samples prior to UVB irradiation led to a significant suppression of cyclobutene pyrimidine dimers (CPD), markers of DNA damage
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