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Polysulfide activates TRP channels and increases intracellular Ca 2+ in astrocytes

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Sometimes, but not always

The precise mechanism of action of phentermine is not entirely understood, but it is believed to exert its effects primarily through the central nervous system by stimulating the release of certain neurotransmitters

Xanax belongs to a class of medicines called benzodiazepines, which work by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity