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And when the skin gets darker, if it's really dark, what we would call it, Addison's disease, right

Recommended injection sites include the abdomen (avoiding a 2-inch radius around the navel), the front of the thighs, and the back of the upper arms

For example, patients taking enzyme-inducing antiepileptic drugs (carbamazepine, phenytoin, and phenobarbital) will clear valproate more rapidly

86 MoriguchiS.TakamiyaA.NodaY.HoritaN.WadaM.TsugawaS.et al (2019)

Essentially, tanning is part of the skins defense mechanism against UV exposure, she explained

T max may have occurred between 2.5 and 16 h, suggesting the pharmacokinetic curve did not capture true C max (Supplementary Figure 8A)