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Insulin amyloid fibril formation reduction by tripeptide stereoisomers
A key aspect of the in vitro work was the meticulous quantification of GSH levels, as well as related markers such as glutathione disulfide, reactive oxygen species (ROS), and adenosine triphosphate (ATP)
PT-141 (bremelanotide): structure and mechanism PT-141, or bremelanotide, is a decyclized version of Melanotan II : same heptapeptide sequence Nle-Asp-His-D-Phe-Arg-Trp-Lys but with a free acid C-terminal end (no amidation) instead of the MT-II-closing lactam bridge
10.1016/j.bbagen.2012.10.012 Biochim
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Endoscopy 42 , 790799 (2010)
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