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219 In addition, AMPK influences histone acetylation by regulating acetyl-CoA metabolism through enzymes such as ACSS2, linking energy status to chromatin remodeling (Fig

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in contrast, micromolar concentrations of the protein are found after cell damage

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Given the limited systematic data on this specific adverse effect, clinicians should maintain awareness that skin symptoms may occur in individual patients, even if not prominently featured in clinical trial safety profiles