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In extreme cases, complications can lead to Stevens-Johnson syndrome or kidney failure
S-adenosylmethionine (SAMe), which serves as a direct precursor to glutathione, is currently being evaluated for its safety, efficacy, and effectiveness in an ongoing phase 4 randomized clinical trial (NCT02024295) for patients with AH and patients with alcohol-associated cirrhosis (NCT04250259)
However, the fatty alteration of hepatocytes in the HF+Lira group was significantly improved
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It is not FDA approval
Halprin KM et al
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