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3.1 GLP-1R agonists in the cardiovascular system GLP-1R is expressed in the heart and vasculature, raising the possibility that GLP-1 might have both direct and indirect actions on the cardiovascular system (Ussher and Drucker, 2023)
Thunders, M
In cells, glutathione is maintained in the reduced form by the enzyme glutathione reductase, which reduces the disulfide form of the molecule (GSSG, glutathione disulfide) back to GSH
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These adaptive mechanisms result in glomerular hyperfiltration and increased glomerular capillary pressure and are associated with kidney injury and hypertension in the long run [150]
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