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Mice exposed to chronic unpredictable mild stress (CUMS) for 6 weeks showed increased hypothalamic corticotropin-releasing hormone concentrations, elevated corticosterone levels and increased blood ammonia, which corresponded with anxiety-like behaviors, demonstrating HPA axis involvement in anxiety pathogenesis (Jia et al., 2024)
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In addition, Ipamorelin may also have a certain therapeutic effect on some diseases related to growth hormone deficiency, such as growth hormone deficiency, dwarfism, etc
Elevated growth hormone may support tissue repair, metabolic regulation, and potentially ovarian follicle quality via IGF1 signaling
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doi: 10.1016/j.scib.2020.12.035 415 TorosantucciA.BromuroC.ChianiP.De BernardisF.BertiF.GalliC.et al
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