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Weeks 5-8: Optimization and Response Assessment The second month represents an optimization phase where protocols may be adjusted based on individual response and tolerance

Bjornsson E, Thorleifsson G, Helgadottir A, Guethnason T, Guethbjartsson T, Andersen K, et al

4.4 Ferroptosis in osteosarcoma Osteosarcoma is a cancerous tumor of the bone characterized by high mortality rates, significant disability, and frequent metastasis and recurrence, primarily affecting the bones and lungs (184)

Besides its role in cancer, amino acid metabolism has been reported as an important participant in the development of metabolic diseases such as diabetes and obesity, as well as cardiovascular diseases, autoimmune diseases and neurological diseases

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