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At the same time, BBR inhibited the oxidative damage induced by H 2 O 2 by down regulating the activities of CAT and SOD and reducing the accumulation of ROS in PIG1 cells, 5 M BBR inhibited the cleavage of PARP and the apoptosis of melanocytes induced by H 2 O 2 by down regulating the ratio of Bax/Bcl-2

Trends Endocrinol Metab (2017) 28(2):88103