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3 It was approved by the US FDA in 2023 to treat obesity (Zepbound , Eli Lilly and Company, Indianapolis, IN, USA) which was initially approved to treat type 2 diabetes in 2022 (Mounjaro , Eli Lilly and Company) (Table 1)

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Together, these compounds are studied for their effects on endogenous GH pulsatility, IGF-1 signaling, visceral fat metabolism, body composition, muscle density, and recovery-related pathways

And while it showed activity on its own, the observed effect appeared greater when combined with another compound such as HA

D.SnijderB.RebsamenM.et al (2015)