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Gut microbiome the trillions of bacteria living in your digestive tract are unique to you, and they play a big role in how your body handles medication Diet before starting a diet already low in fiber or high in processed foods can make the transition harder Your dose level studies show higher doses of semaglutide are associated with more intense GI symptoms, which is why most doctors start low and increase gradually Pre-existing GI conditions if you have IBS, GERD, or other digestive issues, your gut may need more time to adapt Does Ozempic Cause Long-Term Gut Damage

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Those with diabetic retinopathy should be monitored closely, particularly during periods of rapid glycemic improvement, as temporary worsening of retinopathy has been observed

If you can't hit the recommended amount through food (around 25 grams a day for women and 38 for men), a fiber supplement may be worth considering

For the full research record, see the dedicated BPC-157 peptide guide