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That is a remarkable outcome, but the distinction matters: these peptides were not FDA-approved today, and pharmacies are not suddenly authorized to begin compounding them tomorrow
The lower glutamate seen in the present study may therefore not reflect lower excitability, but instead an ongoing energy shortage, perhaps due to the hyperresponsiveness of the occipital cortex typically seen in migraine with aura 37
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The cells were collected after treatment, washed twice with cold phosphate-buffered saline, and treated with 1 mL of cold citrate buffer (0.24 M sucrose, 40 mM sodium citrate, pH 7.6)