Months 1-2 (Initial Titration): Maintain weights from before starting medication Focus on consistent training despite side effects Priority is showing up, not pushing intensity If you miss workouts due to nausea, dont compensate by training harder Months 3-6 (Adaptation Phase): Attempt modest strength increases (2.5-5 pounds on upper body, 5-10 pounds on lower body every 3-4 weeks) If strength stalls, thats acceptable maintenance is success Increase reps before increasing weight (if you can do 12 reps with good form, add weight) Months 7-11 (Maintenance Phase): Continue training at maintained strength levels Accept that weight loss velocity is slowing Focus shifts to body composition refinement Consider adding 1 additional set per exercise if recovery permits MY UNCONVENTIONAL RECOMMENDATION I actually tell patients to stop tracking their one-rep maxes during Retatrutide treatment

Regular, predictable dosing helps maintain stable medication levels in your bloodstream, which translates to more consistent blood glucose control, reduced side effects, and better long-term management of type 2 diabetes
The reduction of Glutathione to form a disulfide bond
Users of Ozempic have similarly reported positive outcomes
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Reduced antioxidative capacity in liver mitochondria from bile duct ligated rats