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5.1 GIP and GLP-1 effects on pancreas 5.1.1 Effects on pancreatic -cell insulin secretion and survival Activation of either GIPR or GLP-1R on pancreatic -cells initiates distinct yet overlapping downstream signaling cascades that ultimately amplify glucose-stimulated insulin secretion

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Ipamorelin is frequently studied alone or in combination with GHRH analogs to evaluate synergistic effects on GH output and downstream IGF-1 signaling

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