HLA-II genes are highly polymorphic due to coexistence with different pathogens as humans moved to different regions, leading to the emergence of new alleles providing resistance to these pathogens [183, 184]
doi: 10.1016/S2666-5247(20)30144-0 249 SchwalfenbergG
Estrogen plays a crucial role in the growth and development of breast tissue, whereas DEHP is able to emulate the natural estrogenic activities, thus interfering with the normal function of the endocrine system 25
By interfering with this binding, it induces apoptosis of senescent cells and promotes their clearance
[] In particular, GSH is known to protect host immune cells, and it is also responsible for the optimal function of the immune system
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